Desktop Printers

ZD421 Series Desktop Printers

Replacing the popular ZD420, the ZD421 is Zebra’s most popular desktop printer series. Choose from either the thermal transfer (ZD421t) or direct thermal (ZD421d) model. 

If you need new communication or media handling options, add serial or Ethernet connectivity, plus a peeler or a cutter, right on site. The optional battery converts the ZD420 printer into a cordless mobile printer, powering it for a full shift when placed on a mobile cart.


Print Width
4.09 in./104 mm for 203 dpi
4.27 in./108 mm for 300 dpi

Maximum Print Speed
6 in./152 mm per second (203 dpi)
4 in./102 mm per second (300 dpi)

Communication Methods
USB v2.0 (Standard)
Bluetooth Low Energy
RS-232 Serial (Option)
10/100 Ethernet (Option)
Wireless: 802.11ac with Bluetooth 4.1 (Factory installed option)

Print Resolution
203 dpi/8 dots per mm
300 dpi/12 dots per mm

Change your ribbon in a matter of seconds

ZD421c – The new Thermal Transfer Cartridge model.

If you are using a thermal transfer printer you know the frustration with changing ribbons. For operators in healthcare or cleanroom manufacturing, changing a ribbon is an undesirable task as they often stain their hands. The ZD421c is the first and only ribbon cartridge printer in the market. Unlike traditional ribbon rolls, the printer alerts you when the ribbon needs replacement and with the cartridge, this can be done in a matter of seconds without contacting the ribbon. Watch the following videos to find out how.

Play Video

Other Models


ZD410 Compact Desktop Printer

The ZD410 is the slimmest direct thermal printer in its class, fitting easily in the most space-constrained work space or shelf. The ZD410 is a direct thermal printer available with either 203 dpi or 300 dpi print resolution. For applications that require a thermal transfer printer, Zebra offers the TLP2824 Plus. 


ZD620 Series Desktop Printers


ZD220 Desktop Printers

ZD220 Direct Thermal/Thermal Transfer Desktop Printer

ZD230 Direct Thermal/Thermal Transfer Desktop Printer